Immune system aberrations in postpartum psychosis: An immunophenotyping study from a tertiary care neuropsychiatric hospital in India
作者： Mahesh M Kumar , Manjunatha M Venkataswamy , Gopinath Sathyanarayanan , Harish Thippeswamy , Prabha S Chandra
DOI: 10.1016/J.JNEUROIM.2017.06.002
关键词:
摘要: Postpartum psychosis (PP) is associated with significant morbidity to both mother and infant. Immune system dysregulation during PP reported in recent studies. This study attempted determine immune signatures first-onset by flow cytometry. Peripheral blood showed decreased naive CD4 CD8 T cells, while activated memory regulatory cells (Tregs) were increased women as against healthy controls. The CD14-CD16+non-classical monocytes, CD11c+myeloid DCs cytotoxic CD56dimCD16+ reduced, CD56brtCD16+/-regulatory NK elevated PP. variations cell subsets highlight the generalized
sci-hub.se 参考文章(30)
Catherine Toben, Bernhard T. Baune, An Act of Balance Between Adaptive and Maladaptive Immunity in Depression: a Role for T Lymphocytes. Journal of Neuroimmune Pharmacology. ,vol. 10, pp. 595- 609 ,(2015) , 10.1007/S11481-015-9620-2
Valerio Chiurchiù, Maria Teresa Cencioni, Elisa Bisicchia, Marco De Bardi, Claudio Gasperini, Giovanna Borsellino, Diego Centonze, Luca Battistini, Mauro Maccarrone, Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis Annals of Neurology. ,vol. 73, pp. 626- 636 ,(2013) , 10.1002/ANA.23875
R. E. Kendell, J. C. Chalmers, C. Platz, Epidemiology of puerperal psychoses British Journal of Psychiatry. ,vol. 150, pp. 662- 673 ,(1987) , 10.1192/BJP.150.5.662
Veerle Bergink, Thaís Armangue, Maarten J. Titulaer, Sander Markx, Josep Dalmau, Steven A. Kushner, Autoimmune Encephalitis in Postpartum Psychosis American Journal of Psychiatry. ,vol. 172, pp. 901- 908 ,(2015) , 10.1176/APPI.AJP.2015.14101332
Holden T. Maecker, J. Philip McCoy, Robert Nussenblatt, Standardizing immunophenotyping for the Human Immunology Project Nature Reviews Immunology. ,vol. 12, pp. 191- 200 ,(2012) , 10.1038/NRI3158
Roosmarijn C. Drexhage, Thomas H. Hoogenboezem, Marjan A. Versnel, Arie Berghout, Willem A. Nolen, Hemmo A. Drexhage, The activation of monocyte and T cell networks in patients with bipolar disorder. Brain Behavior and Immunity. ,vol. 25, pp. 1206- 1213 ,(2011) , 10.1016/J.BBI.2011.03.013
T Okano, J Nomura, R Kumar, E Kaneko, R Tamaki, I Hanafusa, M Hayashi, A Matsuyama, An epidemiological and clinical investigation of postpartum psychiatric illness in Japanese mothers Journal of Affective Disorders. ,vol. 48, pp. 233- 240 ,(1998) , 10.1016/S0165-0327(97)00158-4
R. Kumar, Maureen Marks, Christine Platz, Keiko Yoshida, Clinical survey of a psychiatric mother and baby unit: characteristics of 100 consecutive admissions Journal of Affective Disorders. ,vol. 33, pp. 11- 22 ,(1995) , 10.1016/0165-0327(94)00067-J
Johann Steiner, Roland Jacobs, Benjamin Panteli, Mareike Brauner, Kolja Schiltz, Sabine Bahn, Marlis Herberth, Sabine Westphal, Tomasz Gos, Martin Walter, Hans-Gert Bernstein, Aye Mu Myint, Bernhard Bogerts, Acute schizophrenia is accompanied by reduced T cell and increased B cell immunity European Archives of Psychiatry and Clinical Neuroscience. ,vol. 260, pp. 509- 518 ,(2010) , 10.1007/S00406-010-0098-X
Ganesa Wegienka, Suzanne Havstad, Kevin R. Bobbitt, Kimberley J. Woodcroft, Edward M. Zoratti, Dennis R. Ownby, Christine Cole Johnson, Within-woman change in regulatory T cells from pregnancy to the postpartum period Journal of Reproductive Immunology. ,vol. 88, pp. 58- 65 ,(2011) , 10.1016/J.JRI.2010.06.157