Spinal multifocal amyloidosis derived from wild-type transthyretin.
作者： Takanao Sueyoshi , Mitsuharu Ueda , Akira Sei , Yohei Misumi , Toshinori Oshima
DOI: 10.3109/13506129.2011.582197
关键词:
摘要: AbstractSpinal amyloidosis can occur as a part of systemic or localized amyloidomas. However, the exact pathogenesis spinal remains to be fully understood. Transthyretin (TTR) is an amyloidogenic protein causing two kinds amyloid diseases. One senile (SSA), which caused by wild-type (WT) TTR and primarily affects cardiac functions. The other type familial amyloidosis, mainly induced mutated TTR. We report here first case multifocal derived from WT with radiculomyelopathy destructive spondylosis. data clinical manifestations suggest that patient may develop SSA. Clinical TTR-related vary more than we previously thought. In one candidate precursor proteins for disease.
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