Immunosuppression in pregnant women infected with human immunodeficiency virus
作者： R.J. Biggar , S. Pahwa , H. Minkoff , H. Mendes , A. Willoughby
DOI: 10.1016/0020-7292(90)90367-T
关键词:
摘要: One hundred two pregnant women at high risk of infection with the human immunodeficiency virus (62 who were drug abusers and 40 Haitian origin) prospectively examined for immunologic changes during after pregnancy. Among 63 virus-negative women, levels CD4+ (helper) cells fell to a nadir 8 weeks before delivery rose rapidly just delivery. The level CD8 + (cytotoxic/suppressor) slowly from midpregnancy 37 virus-positive CD4 pregnancy (except transient weak increase delivery) did not recover in postpartum period. Levels consistently higher than women. Post partum stabilized levels, whereas they increased greatly loss appeared be faster These data support hypothesis that may accelerate virus-induced depletion acquired syndrome. (AM J OBSTET GVNECOL 1989;161 :1239-44.)
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