Childhood adversity increases the risk of onward transmission from perinatal HIV-infected adolescents and youth in South Africa.

摘要: Repeated exposure to childhood adversity (abuse, neglect and other traumas experienced before age 18) can have lifelong impacts on health. For HIV-infected adolescents youth, such may include onward transmission of HIV. To evaluate this possibility, the current study measured burden its influence risky health behaviors among perinatally-infected youth. We surveyed 250 youth (13-24 years) receiving care in Soweto, South Africa. Both male female participants reported (using ACE-IQ), sexual behavior, psychosocial state. Viral load was also abstracted from their charts. used logistic regressions test association between cumulative behavioral outcomes. Half sample eight or more adversities. Overall, 72% emotional abuse, 59% physical 34% 82% witnessed domestic violence, 91% saw someone being attacked community. A clear gradient emerged adversities risk. Having one additional raised odds behavior by almost 30% (OR 1.27, 95% CI 1.09-1.48). suppression poor overall (31% had viral loads >400 copies/ml), but not related adversity. Adversity showed a robust relationship depression substance abuse. Childhood is common, influences HIV-positive puts partners at risk for HIV infection. Greater primary prevention increased access support services (e.g., mental health) could reduce taking