Mitochondrial dysfunction induced by fatty acid ethyl esters, myocardial metabolites of ethanol.
作者： L G Lange , B E Sobel
DOI: 10.1172/JCI111022
关键词:
摘要: … principally through a soluble esterase-catalyzed esterification … function of isolated mitochondria, incubations were carried … mM; and ADP, 390 MM, to ensure stability of the mitochondria. …
sci-hub.se 参考文章(15)
Britton Chance, Herrick Baltscheffsky, Respiratory Enzymes in Oxidative Phosphorylation Journal of Biological Chemistry. ,vol. 233, pp. 736- 739 ,(1958) , 10.1016/S0021-9258(18)64738-6
L.G. Lange, S.R. Bergmann, B.E. Sobel, Identification of fatty acid ethyl esters as products of rabbit myocardial ethanol metabolism. Journal of Biological Chemistry. ,vol. 256, pp. 12968- 12973 ,(1981) , 10.1016/S0021-9258(18)42991-2
JOHN G. DEMAKIS, The Natural Course of Alcoholic Cardiomyopathy Annals of Internal Medicine. ,vol. 80, pp. 293- 297 ,(1974) , 10.7326/0003-4819-80-3-293
L. D. SEGEL, S. V. RENDIG, D. T. MASON, Left ventricular dysfunction of isolated working rat hearts after chronic alcohol consumption Cardiovascular Research. ,vol. 13, pp. 136- 146 ,(1979) , 10.1093/CVR/13.3.136
P. Borst, J.A. Loos, E.J. Christ, E.C. Slater, Uncoupling activity of long-chian fatty acids Biochimica et Biophysica Acta. ,vol. 62, pp. 509- 518 ,(1962) , 10.1016/0006-3002(62)90232-9
Ronald Weishaar, Jonnalagedda S.M. Sarma, Yukio Maruyama, Renate Fischer, Silvia Bertuglia, Richard J. Bing, Reversibility of mitochondrial and contractile changes in the myocardium after cessation of prolonged ethanol intake American Journal of Cardiology. ,vol. 40, pp. 556- 562 ,(1977) , 10.1016/0002-9149(77)90071-6
R J Regan, G Koroxenidis, C B Moschos, H A Oldewurtel, P H Lehan, H K Hellems, The acute metabolic and hemodynamic responses of the left ventricle to ethanol. Journal of Clinical Investigation. ,vol. 45, pp. 270- 280 ,(1966) , 10.1172/JCI105340
L. G. Lange, Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase Proceedings of the National Academy of Sciences of the United States of America. ,vol. 79, pp. 3954- 3957 ,(1982) , 10.1073/PNAS.79.13.3954
Victor J. Ferrans, Richard G. Hibbs, Donald G. Weilbaecher, William C. Black, John J. Walsh, George E. Burch, Alcoholic cardiomyopathy a histochemical study American Heart Journal. ,vol. 69, pp. 748- 765 ,(1965) , 10.1016/0002-8703(65)90449-7
Otmar M. Pachinger, Harald Tillmanns, James C. Mao, Jean-Marie Fauvel, Richard J. Bing, The Effect of Prolonged Administration of Ethanol on Cardiac Metabolism and Performance in the Dog Journal of Clinical Investigation. ,vol. 52, pp. 2690- 2696 ,(1973) , 10.1172/JCI107463