Successful treatment with bilateral deep brain stimulation of the subthalamic nucleus for benign tremulous parkinsonism

摘要: A 62-year-old man complained of resting tremor and posture tremor. In spite presence the tremor, other parkinsonian component was very mild. [(11)C]2β-carbomethoxy-3β-(4-fluorophenyl)-tropane ([(11)C]CFT) PET showed asymmetrical reduction uptake [(11)C]raclopride slightly increased in striatum. Although he diagnosed as having benign tremulous parkinsonism (BTP), anti-parkinsonian medications, including anti-cholinergic agent, dopamine agonist l-dopa, were not effective for his His gradually deteriorated enough to disturb writing, working, eating. Because quality life (QOL) disturbed by troublesome deep brain stimulation subthalamic nucleus (STN-DBS) performed. After STN-DBS, dramatically improved. According clinical course our patient well previous reports, STN-DBS should be considered a therapeutic option BTP patients with severe