Correlations of Expression Levels of a Panel of Genes (IRF5, STAT4, TNFSF4, MECP2, and TLR7) and Cytokine Levels (IL-2, IL-6, IL-10, IL-12, IFN-γ, and TNF-α) with Systemic Lupus Erythematosus Outcomes in Jordanian Patients

作者: Amal H. Uzrail , Areej M. Assaf , Shtaywy S. Abdalla

DOI: 10.1155/2019/1703842

关键词:

摘要: … Also, the ratio of IL-10/IL-2 was significantly higher in SLE patients with high disease activity … between plasma levels of IFN-c, IL-2, and IL-12 and IL-10/IL-2 ratio with SLEDAI score. …

参考文章(51)
Mansour F. Karadsheh, Rasha F. Karadsheh, Farah A. Nimri, Wael A. Dneibat, Yousef M. Ajlouni, The characteristics of systemic lupus erythematosus. A study in a general hospital. Saudi Medical Journal. ,vol. 21, pp. 282- 286 ,(2000)
Gunnar Alm, Ann-Christine Syvänen, Lars Rönnblom, Betsy J. Barnes, Di Feng, Rivka C. Stone, Maija-Leena Eloranta, Niquiche Sangster-Guity, Gunnel Nordmark, Snaevar Sigurdsson, Chuan Wang, Genetic variants and disease‐associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus Arthritis & Rheumatism. ,vol. 62, pp. 562- 573 ,(2010) , 10.1002/ART.27223
Esteban Ballestar, Manel Esteller, Bruce C. Richardson, The Epigenetic Face of Systemic Lupus Erythematosus Journal of Immunology. ,vol. 176, pp. 7143- 7147 ,(2006) , 10.4049/JIMMUNOL.176.12.7143
J. Dang, S. Shan, J. Li, H. Zhao, Q. Xin, Y. Liu, X. Bian, Q. Liu, Gene-gene interactions of IRF5, STAT4, IKZF1 and ETS1 in systemic lupus erythematosus. Tissue Antigens. ,vol. 83, pp. 401- 408 ,(2014) , 10.1111/TAN.12349
Patricia López, Carmen Gutiérrez, Ana Suárez, IL-10 and TNFαGenotypes in SLE BioMed Research International. ,vol. 2010, pp. 838390- 838390 ,(2010) , 10.1155/2010/838390
Hanan El-saadany, Manal Abd Elkhalik, Timour Moustafa, Enam Abd El bar, Thyroid dysfunction in systemic lupus erythematosus and rheumatoid arthritis: Its impact as a cardiovascular risk factor The Egyptian Rheumatologist. ,vol. 36, pp. 71- 78 ,(2014) , 10.1016/J.EJR.2013.12.003
Bridget Griffiths, Marta Mosca, Caroline Gordon, None, Assessment of patients with systemic lupus erythematosus and the use of lupus disease activity indices. Best Practice & Research: Clinical Rheumatology. ,vol. 19, pp. 685- 708 ,(2005) , 10.1016/J.BERH.2005.03.010
Karen H. Costenbader, Diane Feskanich, Meir J. Stampfer, Elizabeth W. Karlson, Reproductive and menopausal factors and risk of systemic lupus erythematosus in women. Arthritis & Rheumatism. ,vol. 56, pp. 1251- 1262 ,(2007) , 10.1002/ART.22510
Graciela S. Alarc�n, Gerald McGwin, Alfred A. Bartolucci, Jeffrey Roseman, Jeffrey Lisse, Barri J. Fessler, Holly M. Bastian, Alan W. Friedman, John D. Reveille, , Systemic lupus erythematosus in three ethnic groups: IX. Differences in damage accrual Arthritis & Rheumatism. ,vol. 44, pp. 2797- 2806 ,(2001) , 10.1002/1529-0131(200112)44:12<2797::AID-ART467>3.0.CO;2-9
Sheng-Quan Zhang, Jian-Wen Han, Liang-Dan Sun, Wen-sheng Lu, Xian-Yong Yin, Xue-Jun Zhang, Sen Yang, None, A single-nucleotide polymorphism of the TNFSF4 gene is associated with systemic lupus erythematosus in Chinese Han population Rheumatology International. ,vol. 31, pp. 227- 231 ,(2011) , 10.1007/S00296-009-1247-2