Polynucleotide analogues
作者： A.M. Michelson , M. Grunberg-Manago
DOI: 10.1016/0926-6550(64)90173-2
关键词:
摘要: Abstract The effect of non-operative base analogues in polynucleotides on the ability to stimulate amino acid incorporation has been studied. Internal changes produce an depending nature and quantity “nonsense” base. A single alteration at nucleoside end polymer markedly inhibits incorporation. Base examined include xanthosine, N 1 -methyluridine, -methyl-5-bromouridine, 6 -hydroxyethyladenosine, -hydroxymethyladenosine, -methyladenosine, -acetylcytidine, -hydroxymethylcytidine. Other variations those obtained by treatment polyribonucleotides with hydroxylamine, a water-soluble carbodi-imide, periodate oxidation. behavior certain is sometimes dependent flanking nucleotides. possible explanation for this given.
elsevier.com
sci-hub.se 参考文章(12)
H.G. Windmueller, Nathan O. Kaplan, The preparation and properties of N-hydroxyethyl derivatives of adenosine, adenosine triphosphate, and nicotinamide adenine dinucleotide. Journal of Biological Chemistry. ,vol. 236, pp. 2716- 2726 ,(1961) , 10.1016/S0021-9258(19)61725-4
Marianne Grunberg-Manago, Priscilla J. Ortiz, Severo Ochoa, Enzymic synthesis of polynucleotides. I. Polynucleotide phosphorylase of azotobacter vinelandii. Biochimica et Biophysica Acta. ,vol. 20, pp. 269- 285 ,(1956) , 10.1016/0006-3002(56)90286-4
A.M. Michelson, J. Dondon, M. Grunberg-Manago, The action of polynucleotide phosphorylase on 5-halogenouridine-5′ pyrophosphates Biochimica et Biophysica Acta. ,vol. 55, pp. 529- 540 ,(1962) , 10.1016/0006-3002(62)90986-1
R. Letters, A. M. Michelson, 13. Polynucleotides. Part III. Synthesis of some polyuridylic acid analogues and a survey of anhydride reagents Journal of the Chemical Society (Resumed). pp. 71- 76 ,(1962) , 10.1039/JR9620000071
M. Grunberg-Manago, A.M. Michelson, Polynucleotide analogues II. Stimulation of amino acid incorporation by polynucleotide analogues Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects. ,vol. 80, pp. 431- 440 ,(1964) , 10.1016/0926-6550(64)90145-8
M. S. BRETSCHER, M. GRUNBERG-MANAGO, Polyribonucleotide-directed Protein Synthesis using an E. coli Cell-free System Nature. ,vol. 195, pp. 283- 284 ,(1962) , 10.1038/195283A0
O. W. Jones, E. E. Townsend, H. A. Sober, L. A. Heppel, EFFECT OF CHAIN LENGTH ON THE TEMPLATE ACTIVITY OF POLYRIBONUCLEOTIDES. Biochemistry. ,vol. 3, pp. 238- 246 ,(1964) , 10.1021/BI00890A016
D. W. VERWOERD, H. KOHLHAGE, W. ZILLIG, Specific partial hydrolysis of nucleic acids in nucleotide sequence studies. Nature. ,vol. 192, pp. 1038- 1040 ,(1961) , 10.1038/1921038A0
Heinz Schuster, The reaction of tobacco mosaic virus ribonucleic acid with hydroxylamine Journal of Molecular Biology. ,vol. 3, pp. 447- IN3 ,(1961) , 10.1016/S0022-2836(61)80057-0
G. M. Tener, 2-Cyanoethyl Phosphate and its Use in the Synthesis of Phosphate Esters1 Journal of the American Chemical Society. ,vol. 83, pp. 159- 168 ,(1961) , 10.1021/JA01462A032