Relationship of Biochemical Outcome to Percentage of Positive Biopsies in Men with Clinically Localized Prostate Cancer Treated with Permanent Interstitial Brachytherapy
作者： Thomas J. Guzzo , Brian M. Levin , Richard Lee , Mengye Guo , Zhen Chen
DOI: 10.1016/J.UROLOGY.2007.09.027
关键词:
摘要: OBJECTIVES Recent studies have demonstrated that the percentage of positive prostate needle biopsies (PPBs) is an independent predictor biochemical failure (BF) after radical prostatectomy and external beam radiotherapy. Few confirmed this phenomenon in patients treated with permanent interstitial brachytherapy. We conducted analysis to determine clinical utility PPBs predicting BF brachytherapy for clinically localized cancer. METHODS The pathologic data from 245 hormone-naive Stage T1c-T2cNxM0 cancer who had undergone 1992 2002 at our institution were retrospectively evaluated. PPBs, preimplant prostate-specific antigen, biopsy Gleason score evaluated as predictors risk was calculated using logistic regression models. time assessed Cox proportional hazard models Kaplan-Meier estimates. RESULTS median study cohort 27%. 10.9% those a less than versus 26.2% greater median. A on multivariate (relative 2.3, 95% confidence interval 1.21 4.39, P = 0.011). In time-to-failure models, antigen level, significantly associated BF. CONCLUSIONS Our suggest undergoing along pretreatment level score, useful preoperative parameter
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sci-hub.se 参考文章(17)
Robert W. Galbreath, Gregory S. Merrick, Kent E. Wallner, Edward Adamovich, Wayne M. Butler, Monotherapeutic brachytherapy for clinically organ-confined prostate cancer. The West Virginia medical journal. ,vol. 101, pp. 168- 171 ,(2005)
Thomas L. Jang, Misop Han, Kimberly A. Roehl, Sheila A. Hawkins, William J. Catalona, More favorable tumor features and progression-free survival rates in a longitudinal prostate cancer screening study: PSA era and threshold-specific effects. Urology. ,vol. 67, pp. 343- 348 ,(2004) , 10.1016/J.UROLOGY.2005.08.048
Misop Han, Alan W. Partin, Charles R. Pound, Jonathan I. Epstein, Patrick C. Walsh, Long-term biochemical disease-free and cancer-specific survival following anatomic radical retropubic prostatectomy. The 15-year Johns Hopkins experience. Urologic Clinics of North America. ,vol. 28, pp. 555- 565 ,(2001) , 10.1016/S0094-0143(05)70163-4
Kevin P McMullen, W.Robert Lee, A structured literature review to determine the use of the American Society for Therapeutic Radiology and Oncology consensus definition of biochemical failure Urology. ,vol. 61, pp. 391- 396 ,(2003) , 10.1016/S0090-4295(02)02259-8
Yasuki Goto, Makoto Ohori, Peter T. Scardino, Use of Systematic Biopsy Results to Predict Pathologic Stage in Patients with Clinically Localized Prostate Cancer: A Preliminary Report International Journal of Urology. ,vol. 5, pp. 337- 342 ,(1998) , 10.1111/J.1442-2042.1998.TB00363.X
XIANG GAO, NAJEEB MOHIDEEN, ROBERT C. FLANIGAN, W. BEDFORD WATERS, EVA M. WOJCIK, CINTHIA R. LEMAN, The extent of biopsy involvement as an independent predictor of extraprostatic extension and surgical margin status in low risk prostate cancer: implications for treatment selection. The Journal of Urology. ,vol. 164, pp. 1982- 1986 ,(2000) , 10.1016/S0022-5347(05)66933-9
AV D'Amico, R Whittington, SB Malkowicz, D Schultz, B Silver, L Henry, M Hurwitz, I Kaplan, CJ Beard, JE Tomaszewski, AA Renshaw, A Wein, JP Richie, Investigating the clinical utility of the percent of positive prostate biopsies in predicting PSA outcome following local therapy for patients with clinically localized prostate cancer Prostate Cancer and Prostatic Diseases. ,vol. 3, pp. 259- 264 ,(2000) , 10.1038/SJ.PCAN.4500413
Gregory S. Merrick, Wayne M. Butler, Kent E. Wallner, Robert W. Galbreath, Jonathan H. Lief, Edward Adamovich, Prognostic significance of percent positive biopsies in clinically organ-confined prostate cancer treated with permanent prostate brachytherapy with or without supplemental external-beam radiation. Cancer Journal. ,vol. 10, pp. 54- 60 ,(2004) , 10.1097/00130404-200401000-00011
YAIR LOTAN, SHAHROKH F. SHARIAT, SEYED M. KHODDAMI, HOSSEIN SABOORIAN, KENNETH S. KOENEMAN, JEFFREY A. CADEDDU, ARTHUR I. SAGALOWSKY, JOHN D. MCCONNELL, CLAUS G. ROEHRBORN, THE PERCENT OF BIOPSY CORES POSITIVE FOR CANCER IS A PREDICTOR OF ADVANCED PATHOLOGICAL STAGE AND POOR CLINICAL OUTCOMES IN PATIENTS TREATED WITH RADICAL PROSTATECTOMY The Journal of Urology. ,vol. 171, pp. 2209- 2214 ,(2004) , 10.1097/01.JU.0000127730.78973.FE
Vida S Tigrani, Vivek Bhargava, Katsuto Shinohara, Joseph C Presti, Number of positive systematic sextant biopsies predicts surgical margin status at radical prostatectomy. Urology. ,vol. 54, pp. 689- 693 ,(1999) , 10.1016/S0090-4295(99)00211-3