Characterization of multi-drug resistant Salmonella typhi isolated from Pakistan.
作者： P. M. A. SHANAHAN , K. A. KARAMAT , C. J. THOMSON , S. G. B. AMYES
DOI: 10.1017/S0950268899003453
关键词:
摘要: SUMMARY Thirty-nine strains of Salmonella typhi, isolated in 1995 from four Districts Pakistan, Rawalpindi, Islamabad, Kharian and Jehlem, were catalogued examined. Chromosomal DNA each isolate was digested with XbaI restriction endonuclease subjected to pulsed-field gel electrophoresis. Three clonal variants comprising 17‐19 fragments identified. Antibiotic susceptibility testing identified that 37 the S. typhi resistant chloramphenicol, trimethoprim ampicillin. These antibiotic resistance genes found be located on one plasmids belonging incompatibility group IncHI1 ranging size 150‐175 Kb. The responsible for this case chloramphenicol acetyltransferase (CAT) type I, dihydrofolate reductase (DHFR) VII b-lactamase TEM-1 respectively.
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sci-hub.se 参考文章(28)
P Gabant, P Newnham, D Taylor, M Couturier, Isolation and location on the R27 map of two replicons and an incompatibility determinant specific for IncHI1 plasmids. Journal of Bacteriology. ,vol. 175, pp. 7697- 7701 ,(1993) , 10.1128/JB.175.23.7697-7701.1993
E. J. Threlfall, L. R. Ward, B. Rowe, S. Raghupathi, V. Chandrasekaran, J. Vandepitte, P. Lemmens, Widespread occurrence of multiple drug-resistant Salmonella typhi in India. European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 11, pp. 990- 993 ,(1992) , 10.1007/BF01967788
S. L. Liu, K. E. Sanderson, Rearrangements in the genome of the bacterium Salmonella typhi Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 1018- 1022 ,(1995) , 10.1073/PNAS.92.4.1018
A. S. Mourad, M. Metwally, A. N. El Deen, E. J. Threlfall, B. Rowe, T. Mapes, R. Hedstrom, A. L. Bourgeois, J. R. Murphy, Multiple-drug-resistant Salmonella typhi. Clinical Infectious Diseases. ,vol. 17, pp. 135- 136 ,(1993) , 10.1093/CLINIDS/17.1.135
P. V. Adrian, K. P. Klugman, S. G. B. Amyes, Prevalence of trimethoprim resistant dihydrofolate reductase genes identified with oligonucleotide probes in plasmids from isolates of commensal faecal flora Journal of Antimicrobial Chemotherapy. ,vol. 35, pp. 497- 508 ,(1995) , 10.1093/JAC/35.4.497
K.L. Thong, S.D. Puthucheary, T. Pang, Genome size variation among recent human isolates of Salmonella typhi. Research in Microbiology. ,vol. 148, pp. 229- 235 ,(1997) , 10.1016/S0923-2508(97)85243-6
E Heikkila, L Sundstrom, M Skurnik, P Huovinen, Analysis of genetic localization of the type I trimethoprim resistance gene from Escherichia coli isolated in Finland. Antimicrobial Agents and Chemotherapy. ,vol. 35, pp. 1562- 1569 ,(1991) , 10.1128/AAC.35.8.1562
R S Schwalbe, C W Hoge, J G Morris, P N O'Hanlon, R A Crawford, P H Gilligan, In vivo selection for transmissible drug resistance in Salmonella typhi during antimicrobial therapy. Antimicrobial Agents and Chemotherapy. ,vol. 34, pp. 161- 163 ,(1990) , 10.1128/AAC.34.1.161
S. Nair, C. L. Poh, Y. S. Lim, L. Tay, K. T. Goh, Genome fingerprinting of Salmonella typhi by pulsed-field gel electrophoresis for subtyping common phage types. Epidemiology and Infection. ,vol. 113, pp. 391- 402 ,(1994) , 10.1017/S0950268800068400
Tikki Pang, Zulfiqar A. Bhutta, B.Brett Finlay, Martin Altwegg, Typhoid fever and other salmonellosis: a continuing challenge Trends in Microbiology. ,vol. 3, pp. 253- 255 ,(1995) , 10.1016/S0966-842X(00)88937-4