Risk of progression to eosinophilic esophagitis in patients with asymptomatic esophageal eosinophilia: A retrospective pilot study

摘要: Background and aim As the number of patients with eosinophilic esophagitis (EoE) has increased worldwide, likelihood diagnosing esophageal eosinophilia (EE) in screening endoscopy also increased. Many these EE do not display any symptoms (i.e. they asymptomatic EE: aEE), risk aEE developing EoE yet to be demonstrated. Methods A total 62 250 cases were found endoscopic registries two digestive disease centers context gastric cancer from April 2016 August 2018, reviewed. Results Thirty-seven (0.059%) registries, histories findings successfully traced for 29 them. While 11 (37.9%) did show change findings, 18 (62.1%) exhibited exacerbation. comparison groups showed both relative youth diffuse distribution independent factors progression (P = 0.0034 0.0078, respectively). Of whose progression, 6 developed (5 (17.2%) proton-pump inhibitor (PPI)-responsive EoE, only 1 (3.4%) PPI-resistant EoE). non-EoE an factor 0.0146). Conclusions some symptomatic EE, existence among them was extremely rare. Younger age at first detection are patients.