White matter architecture rather than cortical surface area correlates with the EEG alpha rhythm.

摘要: There are few studies on the neuroanatomical determinants of EEG spectral properties that would explain its substantial inter-individual variability in spite decades biophysical modeling predicts this type relationship. An exception is negative relation between head size and position alpha peak (P(alpha)) reported Nunez et al. (1978)-proposed as evidence influence global boundary conditions slightly damped neocortical waves. Here, we attempt to reexamine finding by computing correlations occipital P(alpha) with various measures cortical surface area, for 222 subjects from EEG/MRI database Cuban Human Brain Mapping Project. No found (p>0.05). On other hand, models also predict white matter architecture, determining time delays connectivities, could have an important P(alpha). This led us explore relations DTI fractional anisotropy means a multivariate penalized regression. Clusters voxels highly significant were found. These positive within Posterior Superior Corona Radiata both hemispheres, supporting theories predicting period cortico-thalamocortical cycles might be modulating frequency. commissural fibers Corpus Callosum present strongest relationships, inferior part (Splenium), connecting lobes superior (Isthmus Tapetum), cortices. We architecture rather than area determines dynamics rhythm.