Developmental changes in spontaneous electrocortical activity and network organization from early to late childhood

摘要: We investigated the development of spontaneous (resting state) cerebral electric fields and their network organization from early to late childhood in a large community sample children. Critically, we examined electrocortical maturation across one-year windows rather than creating aggregate averages that can miss subtle maturational trends. implemented several novel methodological approaches including more fine grained examination spectral features multiple electrodes, use phase-lagged functional connectivity control for confounding effects volume conduction applying topological analyses weighted cortical adjacency matrices. Overall, there were major decreases absolute EEG density (particularly slow wave range) lobes as function age. Moreover, peak alpha frequency increased with chronological age was redistribution relative toward higher ranges, consistent much previous literature. There differences long range brain connectivity, particularly band, culminating most dense spatially variable networks oldest discovered age-related reductions characteristic path lengths, modularity homogeneity alpha-band childhood. In summary, is evidence scale reorganization endogenous childhood, suggesting reduced signal amplitudes presence functionally integrated band limited coordination neuronal activity cortex.