Peak alpha frequency is a neural marker of cognitive function across the autism spectrum.

摘要: Cognitive function varies substantially and serves as a key predictor of outcome response to intervention in autism spectrum disorder (ASD), yet we know little about the neurobiological mechanisms that underlie cognitive children with ASD. The dynamics neuronal oscillations alpha range (6-12 Hz) are associated cognition typical development. Peak frequency is also highly sensitive developmental changes neural networks, which function, therefore, it holds promise developmentally marker Here, measured peak band under task-free condition heterogeneous sample ASD (N = 59) age-matched typically developing (TD) (N = 38). At group level, was decreased compared TD children. Moreover, within group, correlated strongly non-verbal cognition. As reflects integrity our results suggest deviations network development may individuals By shedding light on correlates ASD, findings lay groundwork for considering useful biomarker this population which, turn, will facilitate investigations early markers impairment predictors high risk infants.