Low-grade primary mucosa-associated lymphoid tissue lymphoma of the nasopharynx: clinicopathological study.

摘要: BACKGROUND Malignant tumors of the nasopharynx are always a challenging problem, both from diagnostic and therapeutic standpoint. Most extranodal lymphomas arise in gastrointestinal tract, but other mucosal organs also may be involved, especially upper aerodigestive tract. Nasopharyngeal rare among lymphoma METHODS Twenty-two patients with primary arising mucosa-associated lymphoid tissue have been studied reference to age, sex, clinical symptoms, laboratory finding, radiological histological subtype, immunohistochemistry. RESULTS All were diagnosed histologically as low-grade type its characteristic lymphoepithelial lesions follicular colonization. The tumor cells typically exhibit following immunophenotypes: positive for CD20, CD45RA, proliferating markers bcl-2. It was negative T-cell CD45RO (UCHLI). CONCLUSION Ear, nose, throat surgeons pathologists should aware this avoid misinterpretation set up protocol management.