Physiology and Metabolism in Isolated Viral Septicemia

摘要: • The hypothesis has been advanced that the human systemic septic response is a function of host and not type infecting organism. Metabolic physiologic data from five immunosuppressed transplant recipients with isolated cytomegaloviral sepsis viremia were prospectively evaluated. Serial cultures obtained lung, sputum, urine, wound, blood, invasive lines positive for virus negative bacterial or fungal pathogens. results compared two banks derived either victims multiple trauma without surgical patients early sepsis. Statistically significant differences between nonseptic reference group noted cardiac index, total peripheral resistance, arteriovenous oxygen content difference, consumption, levels triglycerides, proline, phenylalanine, tyrosine, α-aminobutyrate, alanine. No such present these group. Physiologic just before death in three indicated failure transport. It appears to viral agents indistinguishable by metabolic criteria resulting agents. ( Arch Surg 1987;122:21-25)