Gemcitabine plus best supportive care (BSC) vs BSC in inoperable non-small cell lung cancer - a randomized trial with quality of life as the primary outcome
作者： H Anderson , P Hopwood , R J Stephens , N Thatcher , B Cottier
关键词:
摘要: … of gemcitabine + BSC patients (22%) than in BSC alone patients (9%) (P … BSC arm (in 11 domains) than in the BSC arm (one symptom item). There was greater deterioration in the BSC …
openrepository.com
nature.com
idealibrary.com参考文章(24)
P Hopwood, , RJ Stephens, Symptoms at presentation for treatment in patients with lung cancer: implications for the evaluation of palliative treatment. The Medical Research Council (MRC) Lung Cancer Working Party. British Journal of Cancer. ,vol. 71, pp. 633- 636 ,(1995) , 10.1038/BJC.1995.124
RJ Stephens, P Hopwood, DJ Girling, D Machin, Randomized trials with quality of life endpoints: are doctors' ratings of patients' physical symptoms interchangeable with patients' self-ratings? Quality of Life Research. ,vol. 6, pp. 225- ,(1997) , 10.1023/A:1026458604826
N. Thatcher, P. Hopwood, H. Anderson, Improving quality of life in patients with non-small cell lung cancer: research experience with gemcitabine. European Journal of Cancer. ,vol. 33, ,(1997) , 10.1016/S0959-8049(96)00336-X
D Brinkley, Quality of life in cancer trials. BMJ. ,vol. 291, pp. 685- 686 ,(1985) , 10.1136/BMJ.291.6497.685
JR Hardy, T Noble, IE Smith, Symptom relief with moderate dose chemotherapy (mitomycin-C, vinblastine and cisplatin) in advanced non-small cell lung cancer British Journal of Cancer. ,vol. 60, pp. 764- 766 ,(1989) , 10.1038/BJC.1989.355
NM Bleehen, , DJ Girling, P Hopwood, G Lallemand, D Machin, RJ Stephens, AJ Bailey, Randomised trial of four-drug vs less intensive two-drug chemotherapy in the palliative treatment of patients with small-cell lung cancer (SCLC) and poor prognosis British Journal of Cancer. ,vol. 73, pp. 406- 413 ,(1996) , 10.1038/BJC.1996.71
Matti S Aapro, Christophe Martin, Sarah Hatty, GEMCITABINE: A SAFETY REVIEW Anti-Cancer Drugs. ,vol. 9, pp. 191- 202 ,(1998) , 10.1097/00001813-199803000-00001
Stuart J. Pocock, Richard Simon, Sequential Treatment Assignment with Balancing for Prognostic Factors in the Controlled Clinical Trial Biometrics. ,vol. 31, pp. 103- 115 ,(1975) , 10.2307/2529712
C. Langer, A. Barsevick, D. Bruner, C. Grindel, J. Leighton, C. Luckscheiter, C. Bonjo, C. McAleer, 79 Correlation of quality of life (QOL) with survival, treatment response, and anemia in patients with advanced non-small cell lung cancer (NSCLC) treated with carboplatin and paclitaxel Lung Cancer. ,vol. 18, pp. 23- ,(1997) , 10.1016/S0169-5002(97)89358-0
P. Hopwood, R. J. Stephens, D. Machin, Approaches to the analysis of quality of life data: experiences gained from a medical research council lung cancer working party palliative chemotherapy trial. Quality of Life Research. ,vol. 3, pp. 339- 352 ,(1994) , 10.1007/BF00451726