Clinical response of three whitening products having different peroxide delivery: comparison of tray, paint-on gel, and dentifrice

摘要: Objective Comparative clinical research was conducted to evaluate the efficacy and safety of three peroxide-containing tooth whitening products having different peroxide delivery. Methodology A total 43 healthy adults who met entrance criteria were randomly assigned either a dual-phase, anticavity, 1% hydrogen dentifrice with manganese gluconate activator, an 18% carbamide paint-on gel, or 5% professional custom tray system. Following manufacturer's instructions, activated used at least twice daily for two minutes, while gel applied daily. The tray, barrier system experimental control this study, worn continuously six eight hours Tooth color (L*a*b*) measured on maxillary anterior teeth from standard digital images, assessed examination subject report. Results At Day 15, group had significant (p 0.10) improvements baseline deltab*, deltaL*, deltaW*, these barrier-free systems not differing significantly > 0.26) respect any individual composite parameters. sensitivity oral irritation most common findings in groups (there no adverse events group), discontinued treatment early because treatment-related event. Conclusion In head-to-head 14-day testing, low concentration (5% peroxide) barrier-based yielded superior improvement compared delivery systems-an metal activator.