Genetic variability in postoperative nausea and vomiting: A systematic review.

作者: Stefanie Klenke , Ulrich H. Frey

DOI: 10.1097/EJA.0000000000001224

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摘要: Background Postoperative nausea and vomiting (PONV) is the most frequent side effect following anaesthesia. Predisposition to developing PONV multifactorial with patient risk factors anaesthetic techniques both being contributory. However, there also a genetic susceptibility PONV, several studies have aimed identify polymorphisms contributing risk. Objective We summarised previous published investigating contribution Design Systematic review without meta-analysis. Data source searched MEDLINE until June 2019. Eligibility criteria Articles were chosen for when included. Exclusion reviews/meta-analysis/comments, articles not in English language, nonappropriate content (e.g. as primary aim of study, study investigated opioid-induced nausea) or if pharmacogenetic addressing treatment PONV. Results A total 59 screened 14 reviewed including one genome-wide association (GWAS). Seven performed East Asians, seven Caucasians. Seventeen been positively associated at least study. Allele frequency differs widely between ethnicities. Furthermore, anaesthesia regimen postoperative time point which was reported quite different. Only two polymorphisms, CHRM3 rs2165870 KCNB2 rs349358 (both first GWAS), significantly incidence Caucasians independent studies. Conclusion There development Two single nucleotide (SNPs), SNP, seem major influence on incidence, Both SNPs primarily identified GWAS this may lead better understanding disease aetiology. Further high-quality are needed reveal more insights susceptibility, particularly so non-Caucasian

参考文章(54)
Ulrich H. Frey, Christoph Schnee, Marc Achilles, Marie-Therese Silvanus, Joachim Esser, Jürgen Peters, Postoperative nausea and vomiting: The role of the dopamine D2 receptor TaqIA polymorphism. European Journal of Anaesthesiology. ,vol. 33, pp. 84- 89 ,(2016) , 10.1097/EJA.0000000000000320
Nicholas J. Schork, Dani Fallin, Bonnie Thiel, Xiping Xu, Ulrich Broeckel, Howard J. Jacob, Daniel Cohen, The future of genetic case-control studies Advances in Genetics. ,vol. 42, pp. 191- 212 ,(2001) , 10.1016/S0065-2660(01)42023-2
T. Hayase, S. Sugino, H. Moriya, M. Yamakage, TACR1 gene polymorphism and sex differences in postoperative nausea and vomiting Anaesthesia. ,vol. 70, pp. 1148- 1159 ,(2015) , 10.1111/ANAE.13082
Piotr K. Janicki, Ryan Vealey, Jiabin Liu, Jeremiah Escajeda, Marek Postula, Kelli Welker, Genome-wide Association Study Using Pooled DNA to Identify Candidate Markers Mediating Susceptibility to Postoperative Nausea and Vomiting Anesthesiology. ,vol. 115, pp. 54- 64 ,(2011) , 10.1097/ALN.0B013E31821810C7
John D McPherson, Marco Marra, LaDeana Hillier, Robert H Waterston, Asif Chinwalla, John Wallis, Mandeep Sekhon, Kristine Wylie, Elaine R Mardis, Richard K Wilson, Robert Fulton, Tamara A Kucaba, Caryn Wagner-McPherson, William B Barbazuk, Simon G Gregory, Sean J Humphray, Lisa French, Richard S Evans, Graeme Bethel, Adam Whittaker, Jane L Holden, Owen T McCann, Andrew Dunham, Carol Soderlund, Carol E Scott, David R Bentley, Gregory Schuler, Hsiu-Chuan Chen, Wonhee Jang, Eric D Green, Jacquelyn R Idol, Valerie V Braden Maduro, Kate T Montgomery, Eunice Lee, Ashley Miller, Suzanne Emerling, Raju Kucherlapati, Richard Gibbs, Steve Scherer, J Harley Gorrell, Erica Sodergren, Kerstin Clerc-Blankenburg, Paul Tabor, Susan Naylor, Dawn Garcia, Pieter J de Jong, Joseph J Catanese, Norma Nowak, Kazutoyo Osoegawa, Shizhen Qin, Lee Rowen, Anuradha Madan, Monica Dors, Leroy Hood, Barbara Trask, Cynthia Friedman, Hillary Massa, Vivian G Cheung, Ilan R Kirsch, Thomas Reid, Raluca Yonescu, Jean Weissenbach, Thomas Bruls, Roland Heilig, Elbert Branscomb, Anne Olsen, Norman Doggett, Jan-Fang Cheng, Trevor Hawkins, Richard M Myers, Jin Shang, Lucia Ramirez, Jeremy Schmutz, Olivia Velasquez, Kami Dixon, Nancy E Stone, David R Cox, David Haussler, W James Kent, Terrence Furey, Sanja Rogic, Scot Kennedy, Steven Jones, André Rosenthal, Gaiping Wen, Markus Schilhabel, Gernot Gloeckner, Gerald Nyakatura, Reiner Siebert, Brigitte Schlegelberger, Julie Korenberg, Xiao-Ning Chen, Asao Fujiyama, Masahira Hattori, Atsushi Toyoda, Tetsushi Yada, Hong-Seok Park, Yoshiyuki Sakaki, Nobuyoshi Shimizu, Shuichi Asakawa, Kazuhiko Kawasaki, Takashi Sasaki, Ai Shintani, Atsushi Shimizu, Kazunori Shibuya, Jun Kudoh, Shinsei Minoshima, Juliane Ramser, Peter Seranski, Celine Hoff, Annemarie Poustka, Richard Reinhardt, Hans Lehrach, A physical map of the human genome. Nature. ,vol. 409, pp. 934- 941 ,(2001) , 10.1038/35057157
Chin-Chen Chu, Chung-Hsi Hsing, Ja-Ping Shieh, Chih-Chiang Chien, Chiu-Ming Ho, Jhi-Joung Wang, The cellular mechanisms of the antiemetic action of dexamethasone and related glucocorticoids against vomiting. European Journal of Pharmacology. ,vol. 722, pp. 48- 54 ,(2014) , 10.1016/J.EJPHAR.2013.10.008
Stefanie Klenke, Martin Kussmann, Winfried Siffert, The GNB3 C825T polymorphism as a pharmacogenetic marker in the treatment of hypertension, obesity, and depression. Pharmacogenetics and Genomics. ,vol. 21, pp. 594- 606 ,(2011) , 10.1097/FPC.0B013E3283491153
Susan W. Wesmiller, Catherine M. Bender, Susan M. Sereika, Gretchen Ahrendt, Marguerite Bonaventura, Dana H. Bovbjerg, Yvette Conley, Association Between Serotonin Transport Polymorphisms and Postdischarge Nausea and Vomiting in Women Following Breast Cancer Surgery Oncology Nursing Forum. ,vol. 41, pp. 195- 202 ,(2014) , 10.1188/14.ONF.195-202
Seung-Hyun Lee, Joo-Dong Kim, Sol-Ah Park, Chung-Sik Oh, Seong-Hyop Kim, Effects of µ-Opioid Receptor Gene Polymorphism on Postoperative Nausea and Vomiting in Patients Undergoing General Anesthesia with Remifentanil: Double Blinded Randomized Trial Journal of Korean Medical Science. ,vol. 30, pp. 651- 657 ,(2015) , 10.3346/JKMS.2015.30.5.651
Marsha M. Cohen, Peter G. Duncan, Donald P. DeBoer, W. Arnold Tweed, The postoperative interview: assessing risk factors for nausea and vomiting. Anesthesia & Analgesia. ,vol. 78, pp. 7- 16 ,(1994) , 10.1213/00000539-199401000-00004