摘要: Abstract Graft-versus-host disease (GVHD) is a serious complication that occurs after allogeneic bone marrow transplantation and contributes to transplant-related morbidity mortality. Recent advances in the measurement of recipient-specific alloreactivity before grafting have led development vitro assays sufficiently predict occurrence moderate severe acute GVHD. This predicative information provides basis for attempts minimize, or prevent, GVHD by prospective donor selection individualized immunotherapeutic strategies.
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sci-hub.se 参考文章(58)
A.P. Schwarer, Y.Z. Jiang, A.J. Barrett, J.M. Goldman, P.A. Brookes, J.R. Batchelor, R.I. Lechler, Frequency of anti-recipient alloreactive helper T-cell precursors in donor blood and graft-versus-host disease after HLA-identical sibling bone-marrow transplantation The Lancet. ,vol. 341, pp. 203- 205 ,(1993) , 10.1016/0140-6736(93)90067-Q
Vassiliki A. Boussiotis, John G. Gribben, Gordon J. Freeman, Lee M. Nadler, Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance. Current Opinion in Immunology. ,vol. 6, pp. 797- 807 ,(1994) , 10.1016/0952-7915(94)90087-6
E. naparstek, R. Or, A. Nagler, G. Cividalli, D. Engelhard, M. Aker, Z. Gimon, N. Manny, T. Sacks, Z. Tochner, L. Weiss, S. Samuel, C. Brautbar, G. Hale, H. Waldmann, S. M. Steinberg, S. SLAVIN, T-cell-depleted allogeneic bone marrow transplantation for acute leukaemia using Campath-1 antibodies and post-transplant administration of donor's peripheral blood lymphocytes for prevention of relapse British Journal of Haematology. ,vol. 89, pp. 506- 515 ,(1995) , 10.1111/J.1365-2141.1995.TB08356.X
NEENA KAPOOR, In vitro model for detection of alloreactivity between HLA-matched donor-host pairs. Preliminary evaluation as a predictor of graft-versus-host disease. Transplantation. ,vol. 34, pp. 100- 102 ,(1982) , 10.1097/00007890-198208000-00009
ANTHONY P. SCHWARER, YIN ZHENG JIANG, SARAH DEACOCK, PAUL A. BROOKES, A. JOHN BARRETT, JOHN M. GOLDMAN, J. RICHARD BATCHELOR, ROBERT I. LECHLER, Comparison of helper and cytotoxic antirecipient T cell frequencies in unrelated bone marrow transplantation. Transplantation. ,vol. 58, pp. 1198- 1203 ,(1994) , 10.1097/00007890-199412000-00011
SAMANTHA T. FUSSELL, MELISSA DONNELLAN, MARGARET A. COOLEY, CAROLINE FARRELL, Cytotoxic T lymphocyte precursor frequency does not correlate with either the incidence or severity of graft-versus-host disease after matched unrelated donor bone marrow transplantation. Transplantation. ,vol. 57, pp. 673- 676 ,(1994) , 10.1097/00007890-199403150-00008
P. J. Bjorkman, M. A. Saper, B. Samraoui, W. S. Bennett, J. L. Strominger, D. C. Wiley, The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens Nature. ,vol. 329, pp. 512- 518 ,(1987) , 10.1038/329512A0
James L.M. Ferrara, CYTOKINE DYSREGULATION AS A MECHANISM OF GRAFT VERSUS HOST DISEASE Current Opinion in Immunology. ,vol. 5, pp. 794- 799 ,(1993) , 10.1016/0952-7915(93)90139-J
J. den Haan, N. Sherman, E Blokland, E Huczko, F Koning, J. Drijfhout, J Skipper, J Shabanowitz, D. Hunt, V. Engelhard, al. et, Identification of a Graft-versus-Host Disease-associated human minor Histocompatibility antigen. Science. ,vol. 268, pp. 1476- 1480 ,(1995) , 10.1126/SCIENCE.7539551
O Ringdén, M Remberger, J Aschan, P Ljungman, B Lönnqvist, L Markling, Long-term follow-up of a randomized trial comparing T cell depletion with a combination of methotrexate and cyclosporine in adult leukemic marrow transplant recipients. Transplantation. ,vol. 58, pp. 887- 891 ,(1994) , 10.1097/00007890-199410270-00005