Antihemolytic Activities of Green Tea, Safflower, and Mulberry Extracts during Plasmodium berghei Infection in Mice.
作者： Suthin Audomkasok , Waraporn Singpha , Sukanya Chachiyo , Voravuth Somsak
DOI: 10.1155/2014/203154
关键词:
摘要: Malaria-associated hemolysis is associated with mortality in adult patients. It has been speculated that oxidative stress and inflammation induced by malaria parasite are involved its pathophysiology. Hence, we aimed to investigate the antihemolytic effect of green tea, safflower, mulberry extracts against Plasmodium berghei infection. Aqueous crude these plants were prepared using hot water method used for oral treatment mice. Groups ICR mice infected 6 × 106 red blood cells P. ANKA intraperitoneal injection given (500, 1500, 3000 mg/kg) twice a day 4 consecutive days. To assess hemolysis, hematocrit levels then evaluated. Malaria infection resulted hemolysis. However, effects observed treated at dose-dependent manners. In conclusion, aqueous exerted antihemolysis These may work as potential source development variety herbal formulations malarial treatment.
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