IL-6 as a keystone cytokine in health and disease
作者： Christopher A Hunter , Simon A Jones
DOI: 10.1038/NI.3153
关键词:
摘要: … on cells of the immune system and those not of the immune system and often … immunity and the possible advantages of various antagonists of IL-6 and consider how the immunobiology …
nature.com
core.ac.uk
calis.edu.cn 
researchgate.net 参考文章(185)
K. Yasukawa, T. Hirano, Y. Watanabe, K. Muratani, T. Matsuda, S. Nakai, T. Kishimoto, Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. The EMBO Journal. ,vol. 6, pp. 2939- 2945 ,(1987) , 10.1002/J.1460-2075.1987.TB02598.X
M Narazaki, K Yasukawa, T Saito, Y Ohsugi, H Fukui, Y Koishihara, GD Yancopoulos, T Taga, T Kishimoto, Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130 Blood. ,vol. 82, pp. 1120- 1126 ,(1993) , 10.1182/BLOOD.V82.4.1120.BLOODJOURNAL8241120
B. Klein, Z. Y. Lu, J. P. Gaillard, J. L. Harousseau, R. Bataille, Inhibiting IL-6 in human multiple myeloma. Current Topics in Microbiology and Immunology. ,vol. 182, pp. 237- 244 ,(1992) , 10.1007/978-3-642-77633-5_29
H Tilg, E Trehu, MB Atkins, CA Dinarello, JW Mier, Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55 Blood. ,vol. 83, pp. 113- 118 ,(1994) , 10.1182/BLOOD.V83.1.113.113
M Honda, H Suzuki, T Tokunaga, T Kishimoto, K Yasukawa, T Saito, Y Osugi, M Cheng, S Yamamoto, Human soluble IL-6 receptor: its detection and enhanced release by HIV infection. Journal of Immunology. ,vol. 148, pp. 2175- 2180 ,(1992)
Claude Libert, Manuela Cappelletti, Giuseppe Lattanzio, Valeria Poli, Gennaro Ciliberto, Piero Musiani, Massimo Aquilina, Defective development of pristane-oil-induced plasmacytomas in interleukin-6-deficient BALB/c mice American Journal of Pathology. ,vol. 151, pp. 689- 696 ,(1997)
Marcus Diamant, Klaus Rieneck, Nadir Mechti, Xue-Guang Zhang, Morten Svenson, Klaus Bendtzen, Bernard Klein, Cloning and expression of an alternatively spliced mRNA encoding a soluble form of the human interleukin-6 signal transducer gp130. FEBS Letters. ,vol. 412, pp. 379- 384 ,(1997) , 10.1016/S0014-5793(97)00750-3
Pascale Chomarat, Jacques Banchereau, Jean Davoust, A. Karolina Palucka, IL-6 switches the differentiation of monocytes from dendritic cells to macrophages Nature Immunology. ,vol. 1, pp. 510- 514 ,(2000) , 10.1038/82763
Richard A. O'Connor, Stefan Floess, Jochen Huehn, Simon A. Jones, Stephen M. Anderton, Foxp3+ Treg cells in the inflamed CNS are insensitive to IL‐6‐driven IL‐17 production European Journal of Immunology. ,vol. 42, pp. 1174- 1179 ,(2012) , 10.1002/EJI.201142216
S. John Curnow, Dagmar Scheel-Toellner, Will Jenkinson, Karim Raza, Omar M. Durrani, Jeff M. Faint, Saaeha Rauz, Kaska Wloka, Darrell Pilling, Stefan Rose-John, Christopher D. Buckley, Philip I. Murray, Mike Salmon, Inhibition of T cell apoptosis in the aqueous humor of patients with uveitis by IL-6/soluble IL-6 receptor trans-signaling. Journal of Immunology. ,vol. 173, pp. 5290- 5297 ,(2004) , 10.4049/JIMMUNOL.173.8.5290