Comparative Aspects of the Structure and Function of Phosphoglucomutase

摘要: Publisher Summary Total amino acid sequence analysis has proved to be a powerful tool for the study of evolution and phylogenetic comparison proteins. Studies have been conducted with hemoglobin cytochrome c. Hemoglobin is confined vertebrates, no bacterial cytochrome, from its properties, would suggest it as genetically homologous c yeast higher plant or animal forms. Criteria other than applied in characterization aldolase, triose phosphate dehydrogenase, lactic dehydrogenase diverse sources. The present studies were undertaken identify protein that, all living forms, expression gene. Phosphoglucomutase seemed offer several advantages such study. reaction that catalyzes—where glucose 1-phosphate converted 6-phosphate—was presumed biologically ubiquitous, preliminary formation, glucose, compounds uridine diphosphate glucose. Therefore, must occur and, because represents major metabolic activity, responsible enzyme should relatively abundant.