Natural History of Helicobacter pylori Infection in Childhood: Eight‐Year Follow‐Up Cohort Study in an Urban Community in Northeast of Brazil

摘要: Background: Helicobacter pylori infection is acquired predominantly in childhood. There also evidence that children loss the infection. Therefore, factors account for remain infected need to be investigated because once established persists throughout life unless treated. Methods: This study aimed evaluate H. of a low-income community at baseline and 8 years later determine predictor linked maintenance, acquisition, using regression models generalized estimating equations. status was determined by 13 C-urea breath test. Results: Data from 37.7% (133 ⁄ 353) were available. No difference between characteristics included nonincluded observed. The prevalence increased 53.4 64.7%. Thirty-nine (29.3%) remained noninfected, 47.4% infected, 17.3% became 6.0% lost Factors associated with compared noninfected age, number household, use well water instead municipal water. acquisition male gender. Conclusion: gain poor region household Also, rates higher than rates, which lead an increase age.