Inhibitors of lysine specific demethylase-1
作者： Jeffrey Alan Stafford , Toufike Kanouni , Young K. Chen , James Marvin Veal , Stephen W. Kaldor
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摘要: The present invention relates generally to compositions and methods for treating cancer neoplastic disease. Provided herein are substituted heterocyclic derivative compounds pharmaceutical comprising said compounds. subject useful inhibition of lysine specific demethylase-1. Furthermore, the treatment cancer, such as prostate breast bladder lung and/or melanoma like.
google.de 参考文章(76)
Hans Bundgaard, Design of prodrugs Elsevier , Sole distributors for the USA and Canada, Elsevier Science Pub. Co.. ,(1985)
Kwang Keun Joseph Shin, Jang Yeol Yoon, Lane keeping assist system and method ,(2013)
Jutta Kirfel, Roland Schüle, Eric Metzger, Reinhard Büttner, Lysine-specific demethylase 1 (lsd1) is a biomarker for breast cancer ,(2010)
Peter A. Blomgren, Douglas G. Stafford, Kevin S. Currie, Aaron C. Schmitt, Pavel E. Zhichkin, Jianjun Xu, Scott A. Mitchell, Seung H. Lee, Jeffrey E. Kropf, Zhongdong Zhao, Substituted amides, methods of making, use thereof for the treatment of diseases such as cancer ,(2008)
Vater Wulf, Bossert Friedrich, Cyanophenyl-1,4-dihydropyridine derivatives ,(1970)
Herbert O. House, Modern Synthetic Reactions ,(1972)
Richard A. Walgren, Christopher A. Slapak, Failure Modes in Anticancer Drug Discovery and Development Cancer Drug Design and Discovery. pp. 567- 581 ,(2014) , 10.1016/B978-0-12-396521-9.00019-X
He Zhao, Jun Yuan, Shaojing Hu, Hongbin Li, Qin Guo, Jianmin Mao, Darren Whitehouse, Jack Hammer, David Wustrow, Wallace Fringle, George Maynard, Subtituted heteroaryl cb1 antagonists ,(2006)
John Charles Stowell, Intermediate Organic Chemistry ,(1988)
Erich Metzger, Reinhard Buettner, Roland Schuele, Antibodies For Use in Identifying and/or Scoring Prostate Cancer and Androgen Receptor-Dependent Gene Expression Control ,(2006)