Phylogenetic analysis of the haemagglutinin gene of current wild-type canine distemper viruses from South Africa: lineage Africa.

作者: Timothy Y. Woma , Moritz van Vuuren , Ana-Mari Bosman , Melvyn Quan , Marinda Oosthuizen

DOI: 10.1016/J.VETMIC.2009.11.013

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摘要: Abstract There are no reports of CDV isolations in southern Africa, and although is said to have geographically distinct lineages, molecular information African strains has not yet been documented. Viruses isolated cell cultures were subjected reverse transcription-polymerase chain reaction (RT-PCR), the complete H gene was sequenced phylogenetically analysed with other from GenBank. Phylogenetic comparisons isolates different parts world (available GenBank) wild-type South revealed nine clades. All form a separate clade their own thus clearly separated American, European, Asian, Arctic vaccine virus It likely that only ‘African lineage’ may be circulating Africa currently, viruses dogs vaccinated against result reversion virulence strains, but infection strains.

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