Insulin Dependent and Independent Actions of Dietary Protein on in Vitro Protein Synthesis in Skeletal Muscle of Rats

摘要: Insulin dependency of the effect dietary protein on in vitro synthesis skeletal muscle was studied rats. Re-feeding fasted rats with an adequate diet caused increase synthetic activity within only 5 hours a concomitant concentration polyribosomes. During re-feeding protein-free increased significantly but it somewhat lower than fed diet. The insulin plasma promptly and markedly when were re-fed either these diets. However, degree slightly less protein-containing meal. normal egg albumin alone, after fasting 1 day, produced marked parallel proportion polyribosomes tissue. stimulatory action not abolished even streptozotocin-diabetic there no appreciable change ribosomal profile diabetic These results indicate that function regulating is mediated entirely by insulin.