Phenotyping Before Starting Treatment in COPD

摘要: Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and complex disease with great morbidity mortality. Despite the new developments in managements of COPD, it was recognized that not all patients benefit from available medications. Therefore, efforts to identify subgroups or phenotypes had been made order predict who will respond class drugs for COPD. This review discuss phenotypes, endotypes, such as frequent exacerbator, one systemic inflammation, fast decliner, ACOS, co-morbidities their impact on therapy. It became apparent, "inflammatory" phenotypes: chronic bronchitic, those number need inhaled corticosteroids; contrast, emphysematous type dyspnea lung hyperinflation, dual bronchodilation (deflators). However, larger, well designed studies clustering COPD are needed, important thus, lead personalize management