Zytologische Beobachtungen an der hyperplastischen Nebennierenrinde des Menschen

作者: Kurt Holzmann , Rainer Lange

DOI: 10.1007/BF00406269

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摘要: Clinical observations and the light electron microscopic appearance of adrenal cortex are described in a case Cushing's disease associated with adrenocortical hyperplasia basophilic adenoma pituitary gland. The investigation concentrates upon occurrence osmiophil material different cytoplasmic compartments cell type rich organelles relatively poor paraplasmic inclusions. It seems that observation perinuclear space, mitochondrial matrix, Golgi vacuoles, vesicles has been made possible by rather long fixation Wohlfarth-Bottermann's chromium-osmium fixative. Mitochondria related particles (named X-Einschlusse) may contain center few dense filaments masses resembling those other authors as being deoxyribonucleic acid nature. Relatively large complexes found, sometimes close topographic relation centriole. A population bodies (lipid droplets, pigment granules, microbodies) is described. Apart from these findings organization tissue studied similar to mammals. discussed respect hypotheses about lipid droplet formation possibility artifacts due preparation procedures.

参考文章(21)
Mollen Hauer Hh, Race Gj, Ashworth Ct, Study of functional activit of adrenocortical cells with electron microscopy. American Journal of Pathology. ,vol. 35, pp. 425- 437 ,(1959)
Ch. Rouiller, Physiological and pathological changes in mitochondrial morphology. International Review of Cytology-a Survey of Cell Biology. ,vol. 9, pp. 227- 292 ,(1960) , 10.1016/S0074-7696(08)62748-5
David D. Sabatini, Eduardo D.P. De Robertis, Ultrastructural zonation of adrenocortex in the rat. Journal of Cell Biology. ,vol. 9, pp. 105- 119 ,(1961) , 10.1083/JCB.9.1.105
Takeo Yamori, Satoru Matsuura, Sakae Sakamoto, An electronmicroscopic study of the normal and stimulated adrenal cortex in the rat. Cell and Tissue Research. ,vol. 55, pp. 179- 199 ,(1961) , 10.1007/BF00340929
Margit M. K. Nass, Sylvan Nass, INTRAMITOCHONDRIAL FIBERS WITH DNA CHARACTERISTICS: I. Fixation and Electron Staining Reactions Journal of Cell Biology. ,vol. 19, pp. 593- 611 ,(1963) , 10.1083/JCB.19.3.593
Jeffrey D. Lever, Electron microscopic observations on the adrenal cortex American Journal of Anatomy. ,vol. 97, pp. 409- 429 ,(1955) , 10.1002/AJA.1000970304
Giuseppe Millonig, A MODIFIED PROCEDURE FOR LEAD STAINING OF THIN SECTIONS The Journal of Biophysical and Biochemical Cytology. ,vol. 11, pp. 736- 739 ,(1961) , 10.1083/JCB.11.3.736
Ian Carr, The ultrastructure of the human adrenal cortex before and after stimulation with ACTH The Journal of Pathology and Bacteriology. ,vol. 81, pp. 101- 106 ,(1961) , 10.1002/PATH.1700810112