Evaluation of a Protocol for Post-Mortem Examination of Stillbirths

作者: Robert F. Mueller , Virginia P. Sybert , Jennifer Johnson , Zane A. Brown , Wei-Jen Chen

DOI: 10.1056/NEJM198309083091004

关键词:

摘要: A variety of procedures have been recommended for post-mortem examination stillbirths to determine the cause loss pregnancy and provide an estimate risk recurrence. We studied relative usefulness several such techniques, including gross microscopical autopsy, photography, radiography, bacterial cultures, chromosome studies. In 44 (35 per cent) 124 cases stillbirth or early neonatal death, structural physical abnormalities were evident at autopsy. 35 due chromosomal, single-gene, polygenic disorders. The single most useful was Analysis various suggests that when resources are limited, cultures should be performed in all but karyotyping histopathology may used selectively. This approach minimize use expensive, low-yield without compromising ability information purposes genetic counseling.

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