Optimizing Recovery, Utilization and Transplantation Outcomes for Kidneys From Small, ≤20 kg, Pediatric Donors

摘要: The optimal balance between maximizing the number versus outcome of transplantation utilizing kidneys from small (≤20 kg) pediatric donors remains unclear, complicated by choice single en bloc with their attendant technical risks. Using Organ Procurement and Transplantation Network (OPTN) database, we examined kidney recovery utilization patterns, 1-year transplant outcomes kilogram weight strata. Between January 1, 2005 June 30, 2010, 2352 ≤20 kg were transplanted into 1531 recipients, 710 transplants (SKTs) 821 (EBKTs). Increased donor was associated higher rates recovery, SKT. Low (linear p < 0.001; quadratic = 0.003), SKT EBKT (p 0.008), increased cold ischemia time local nonlocal 0.0044), low high volume center 0.003) interaction term 0.0024) graft failure. Notably, lower exacerbated negative impact but did not worsen on outcomes. Our data show that offers superior survival at expense accomplishing one rather than two transplants. However, SKTs yield excellent when performed experienced centers.