Research perspectives: gold nanoparticles in cancer theranostics.

摘要: High recurrence rates after surgical resection remain a formidable challenge in many cancers. Although chemo- and/or radiotherapy are often applied following surgery to prevent tumor relapse, these treatments generally accompanied by serious side effects and challenges their delivery that limit effectiveness. Gold nanoparticles (AuNPs), which possess unique physicochemical properties, have the potential enhance efficacy of conventional treatment modalities. In this review, we briefly describe current state AuNP research area cancer theranostics. Recent studies investigated AuNPs’ use as photothermal converters, drug carriers, radiosensitizers, imaging probes wide range applications for diagnosis therapy. AuNPs promise minimally invasive thermal ablation therapy, diagnostic imaging, intraoperative margin delineation, multimodal anticancer The successful translation into clinic will significant impact on care patients using image-guided, approaches.