Assessing the potential of mesenchymal stem cells in craniofacial bone repair and regeneration

摘要: Bone tissue regeneration is required in clinical procedures such as maxillary sinus floor lift, lateral alveolar augmentation to increase the width of mandible, and vertical height mandible. grafts contain a reservoir cells involved repair process, including mesenchymal stem (MSCs), but also “cocktail” growth factors embedded within an extracellular matrix (ECM). Rapid bone healing often goal for craniofacial tissues, this ideally achieved by primary involving predominantly intramembranous ossification where revascularised synthesis facilitate process. When considering natural haematoma, granulation tissue, osteoid all support 3D ECM structure. These scaffolds provide spatial arrangement facilitating cell focal contacts delivery surface receptors.