Allergen-induced Recruitment of Bronchoalveolar Helper (OKT4) and Suppressor (OKT8) T-Cells in Asthma: Relative Increases in OKT8 Cells in Single Early Responders Compared with Those in Late-Phase Responders
作者： M. Cristina Gonzalez , Patricia Diaz , F. R. Galleguillos , Patricia Ancic , O. Cromwell
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摘要: We measured the numbers of helper (OKT4) and suppressor (OKT8) T-cells in blood bronchoalveolar lavage (BAL) 6 patients who developed single early reactions after allergen inhalational challenge subjects dual (early- late-phase) responses. The asthmatics were lavaged twice. On first occasion, they inhaled diluent control (Dil) solution, an interval at least 7 days, (Ag) was undertaken. Significant differences observed responders (SER) only. For instance, when results obtained on Dil day compared with those Ag day, there a significant (p < 0.05) increase percentage OKT4 cells SER. Also BAL SER decrease absolute OKT8 cells. Furthermore, highly significantly 0.005) lower Ag...
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