Advanced gastric cancer with liver and lymph node metastases successfully resected after induction chemotherapy with docetaxel, cisplatin and 5-fluorouracil.

摘要: Background: At diagnosis, about 35% of patients with gastric cancer present distant metastases, and most liver metastases are excluded from curative surgery. Case: We report a case human epidermal growth factor receptor-2 (HER2)-negative to the perigastric lymph nodes. The patient (a 60-year-old man) was considered unresectable at diagnosis treated palliative chemotherapy (docetaxel plus cisplatin 5-fluorouracil by continuous intravenous infusion over 5 days every 3 weeks). However, after 6 courses chemotherapy, computed tomography scan showed reduction metastasis disappearance enlarged then underwent gastrectomy, lymphadenectomy resection. After surgery, FOLFOX-4 regimen as adjuvant chemotherapy. With follow-up 26 months is alive disease free. Conclusion: In metastatic cancer, prognosis poor median overall survival 11 since treatments excluded; however, this illustrated that personalized treatment surgery can allow strategy in selected HER2-negative advanced cancer.