Comparison of Safety and Efficacy of Different Models of Target Vessel Regional Chemotherapy for Gastric Cancer with Liver Metastases.

摘要: Background/Aims: We previously demonstrated the safety and efficacy of low-dose, short-interval target vessel regional chemotherapy (TVRCLDSI) delivered through hepatic artery with transarterial embolization (TAE) in patients advanced gastric cancer (AGC). The present study aimed to compare TAE + TVRCLDSI that standard TVRC AGC liver metastases who failed respond first- or second-line systemic chemotherapy. Methods: This recruited a total 58 GC after failure Twenty-eight were assigned group 30 group. primary end point was overall survival (OSTVRC), which defined as time from initiation until last follow-up death. Results: OSTVRC, progression (TTP) appearance intra- extrahepatic metastases, TTP treatment periods all significantly longer than (all p Conclusion: had higher safety, reflected by OS rates, progression-free duration milder side effects compared TVRC.