Which nucleoside and nucleotide backbone combinations select for the K65R mutation in HIV-1 reverse transcriptase.

作者: Alan Winston , Anton Pozniak , Sundhiya Mandalia , Brian Gazzard , Deenan Pillay

DOI: 10.1097/00002030-200404090-00014

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摘要: The K65R mutation has been reported to be associated with the use of abacavir, didanosine and tenofovir. With advent tenofovir we have assessed change in prevalence this mutation. remains low, but significantly increased over a 2-year period. Although not specific drug, it is dual tenofovir, triple combination abacavir.

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