Hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II): A common genotype linked to oncogenes?
作者： Henry T. Lynch , Jane F. Lynch
DOI: 10.1016/0306-9877(85)90115-X
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摘要: Abstract We hypothesize that: 1) hereditary non polyposis colorectal cancer (HNP CC) accounts for a significant proportion of the colon burden; 2) premalignant colonic mucosa in HNP CC patients may be comparable many respects to polyps its multiple adenomatous counterpart; and finally, 3) study harbor important clues elucidation multistep process carcinogenesis, including relationships between activated oncogenes, genetics, environmental perturbations.
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W. E. Heston, Genetics: Animal Tumors Springer, Boston, MA. pp. 33- 57 ,(1975) , 10.1007/978-1-4613-4449-0_2
Joan E. Bailey-Wilson, Robert C. Elston, Guy S. Schuelke, William Kimberling, William Albano, Jane F. Lynch, Henry T. Lynch, D. C. Rao, Segregation analysis of hereditary nonpolyposis colorectal cancer Genetic Epidemiology. ,vol. 3, pp. 27- 38 ,(1986) , 10.1002/GEPI.1370030104
Kazymir M. Pozharisski, Alexei J. Likhachev, Valeri F. Klimashevski, Jacob D. Shaposhnikov, Experimental Intestinal Cancer Research with Special Reference to Human Pathology Advances in Cancer Research. ,vol. 30, pp. 165- 237 ,(1979) , 10.1016/S0065-230X(08)60897-0
Pelayo Correa, William Haenszel, The epidemiology of large-bowel cancer. Advances in Cancer Research. ,vol. 26, pp. 1- 141 ,(1978) , 10.1016/S0065-230X(08)60086-X
MARTIN J. CLINE, Oncogenes: Implications for the Diagnosis and Treatment of Cancer Annals of Internal Medicine. ,vol. 101, pp. 223- 233 ,(1984) , 10.7326/0003-4819-101-2-223
Alain P. Maskens, Rose-Marie Dujardin-Loits, Experimental adenomas and carcinomas of the large intestine behave as distinct entities: Most carcinomas arisede novo in flat mucosa Cancer. ,vol. 47, pp. 81- 89 ,(1981) , 10.1002/1097-0142(19810101)47:1<81::AID-CNCR2820470115>3.0.CO;2-T
M Lipkin, B S Reddy, J Weisburger, L Schechter, Nondegradation of Fecal Cholesterol in Subjects at High Risk for Cancer of the Large Intestine Journal of Clinical Investigation. ,vol. 67, pp. 304- 307 ,(1981) , 10.1172/JCI110027
E Santos, D Martin-Zanca, E. Reddy, M. Pierotti, G Della Porta, M Barbacid, Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient Science. ,vol. 223, pp. 661- 664 ,(1984) , 10.1126/SCIENCE.6695174
Paul Rozen, Shlomo M. Hellerstein, Crystal Horwitz, The low incidence of colorectal cancer in a “high-risk” population: Its correlation with dietary habits Cancer. ,vol. 48, pp. 2692- 2695 ,(1981) , 10.1002/1097-0142(19811215)48:12<2692::AID-CNCR2820481222>3.0.CO;2-L
B. Shannon Danes, Increased in vitro tetraploidy: tissue specific within the heritable colorectal cancer syndromes with polyposis coli. Cancer. ,vol. 41, pp. 2330- 2334 ,(1978) , 10.1002/1097-0142(197806)41:6<2330::AID-CNCR2820410635>3.0.CO;2-X