ANGIO-IMMUNOBLASTIC LYMPHADENOPATHY WITH DYSPROTEINÆMIA

摘要: Abstract A new disease with a lymphoma-like Summary clinical presentation and specific histological picture has been recognised in fifteen patients. Clinically, the disease, which seems to occur chiefly elderly, is characterised by an acute onset of constitutional symptoms, generalised lymphadenopathy, hepatosplenomegaly, immunological abnormalities. The course stormy, but one third reported cases it may have controlled immunosuppressants; severe infectious complications are common often fatal. Histologically, diffuse obliteration nodal architecture due pronounced proliferation small vessels immunoblasts distinctive feature; there similar spleen, bone-marrow, liver, skin. Biopsy specimens necropsy material indicate that non-neoplastic process. evolution, widespread organ involvement, pattern very those graft-versus-host reaction.