作者: Elisabeth Fayard , Lionel A Tintignac , Anne Baudry , Brian A Hemmings
DOI: 10.1242/JCS.02724
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摘要: Among the signalling proteins that respond to a large variety of signals, protein kinase B (PKB, also known as Akt) appears be central player in regulation metabolism, cell survival, motility, transcription and cell-cycle progression. Conserved from primitive metazoans humans, PKB belongs