Racial disparities in histopathologic characteristics of uterine cancer are present in older, not younger blacks in an equal-access environment☆

作者: Kate E. Oliver , Lindsey R. Enewold , Kangmin Zhu , Thomas P. Conrads , G. Scott Rose

DOI: 10.1016/J.YGYNO.2011.06.027

关键词:

摘要: article i nfo Objective. We sought to determine whether racial disparities in tumor characteristics among uterine cancer patients persisted, and varied by age, an equal-access healthcare population. Methods. The distributions of histology, stage grade race were compared for cancers diagnosed from 1990 2003 using data the U.S. Department Defense's Automated Central Tumor Registry. Comparisons conducted overall stratified age (b50, ≥50) Chi-square test. Results. Of 2582 tumors identified, 2057 (79.7%) White women 183 (7.1%) Black women. Among all analyzed, Blacks more likely than Whites present with non-endometrioid tumors(47.7%vs 23.5%,pb0.01),non-localized tumors(31.8% vs 24.5%, p=0.02),andpoorly differentiated (20.5% 15.0%, pb0.01). 50 years older, similar significant disparitieswereobserved.However,nosignificantracialdifferenceswereobservedamongyoungpatients.When comparisons restricted endometrioid histology adenocarcinomas, trends age-specific older observed. Conclusions. Our study suggests that persist between endure higher tumors, aggressive histologies. This disparity clinicopathologic factors is confined years. Multiple such as variation age-related health knowledge/behavior estrogen metabolism may be related disparity.

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