Parameters of in vitroEvolution of Proteins and Peptides
作者： V. P. Valuev , D. A. Afonnikov , O. I. Petrenko , D. A. Grigorovich
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摘要: In vitroevolution is used to study protein sequences, structures, and interactions obtain proteins with new properties. To analyze the specific features of this process in phage display experiments, we studied amino acid composition selected constructed a matrix substitutions, identified pairs coadaptive substitutions. The frequency proved be tightly associated number corresponding codons; numerous correlated substitutions were found.
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