摘要: The genetic differences that potentially account for the attenuation of Oka vaccine VZV preparation are more clearly defined than perhaps any other in current use. This is due large part to small number between and parental strain from which it was derived, high level genomic conservation characterizes VZV. information has been used with great success develop methods discriminate wild-type strains, begin determining specific markers contribute attenuated phenotype, improve evaluations efficacy safety, observe behavior live, as becomes prevalent through widespread immunization.
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