作者: Alper Çelik , I. Ebru Arabacı , Unal Erkorkmaz , Suat Kutun , Sabahattin Aslan
DOI: 10.2478/S11536-007-0006-6
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摘要: We aimed to investigate the correlation between quantitative CerbB-2 expressions with conventional prognostic factors, and distinct nodal involvement in patients invasive breast carcinoma. One hundred fifty seven consecutive carcinoma were retrospectively analysed. Level I–II, III, Rotter (Interpectoral) group lymph nodes separately examined recorded. For each patient estrogen receptor (ER), progesteron (PR), CerbB-2, P53 status defined using immunohistochemistry. Age, tumor localisation, menopausal status, grade presence of intraductal component also expression did not correlate age, localisation status. There was a reverse, but weak size (p=0.034). In subgroup analysis positive cases, magnitude positivity (p=0.551). univariate I-II, Rotter. linearly increased number this difference significant (p=0,039). III metastases (p=0.005). But among (p=0.82). P53, PR differ according oncogene expression. detected reverse ER (p=0.011). It is concluded that CerbB2 increases I–II axillary nodes, ER. Also, more common node metastases.