Risk Factors of Synchronous Inguinal Lymph Nodes Metastasis for Lower Rectal Cancer Involving the Anal Canal

摘要: Purpose The aim of the study is to identify risk factors synchronous ILN metastasis for lower rectal cancer involving anal canal. Methods Patients with who underwent radical resection at Fudan University Shanghai Cancer Center were retrospectively analyzed. The was defined as occurring within 6 months after diagnosis cancer. Patients’ gender, age, tumor diameter, dentate line invasion, differentiation level, histological type, depth perirectal LN metastasis, lymphovascular invasion or perineural analyzed in study. correlation between involvement and clinicopathological features Chi-square test/fisher’s exact test. Variables p<0.05 univariate analysis then a multivariate logistic model. Odds ratio (OR) along 95% confidence intervals (95% CI) calculated. Results A total 325 patients (182 men 143 women) met criteria enrolled Among them, 20 (6.2%) had metastasis. Both showed strong odds 23.558 [95% interval (CI) 6.380–86.982] (p<0.001). presence also significant 5.260 1.818–15.212] (p = 0.002). Conclusions are two independent inguinal lymph node canal.