The influence of osteoporotic fractures on health-related quality of life in community-dwelling men and women across Canada.

摘要: Health-related quality of life (HRQL) was examined in relation to prevalent fractures 4816 community-dwelling Canadian men and women 50 years older participating the Multicentre Osteoporosis Study (CaMos). Fractures were three categories: clinically recognized main fractures, subclinical vertebral at other sites. Main divided analyzed hip, spine, wrist/forearm, pelvis rib Baseline assessments anthropometric data, medical history, therapeutic drug use, spinal radiographs obtained from all participants. The SF-36 instrument used as a tool measure HRQL. A total 652 (13.5%) reported. Results indicated that had occurred 78 (1.6%), 40 (0.8%), 390 (8.1%), 19 (0.4%) 125 (2.6%) individuals, respectively (subjects may have more than one fracture). Subjects who experienced fracture lower HRQL scores compared with non-fractured largest differences observed physical functioning (−4.0; 95% confidence intervals (CI): −6.0, −2.0) role-physical domains (−5.8; CI: −9.5, −2.2). In women, domain most influenced by hip (−14.9%; −20.9, −9.0) (−18.1; −27.6, −8.6) fractures. men, affected (−35.7; −60.4, −11.1). those without conclusion, sustained hip. Subclinical exerted moderate effect on