The Role of Oxidative Stress in Neurodegenerative Diseases

摘要: Oxidative stress is induced by an imbalanced redox states, involving either excessive generation of reactive oxygen species (ROS) or dysfunction the antioxidant system. The brain one organs especially vulnerable to effects ROS because its high demand and abundance peroxidation-susceptible lipid cells. Previous studies have demonstrated that oxidative plays a central role in common pathophysiology neurodegenerative diseases such as Alzheimer's disease Parkinson's disease. Antioxidant therapy has been suggested for prevention treatment diseases, although results with regard their efficacy treating inconsistent. In this review, we will discuss vivo measurement index damage stress. Moreover, present knowledge on future directions be outlined.