The simultaneous boost technique: the concept of relative normalized total dose.

摘要: The simultaneous boost technique in radiotherapy consists of delivering the treatment (additional doses to reduced volumes) simultaneously with basic (large-field) for all sessions. Both dose per fraction delivered by basic-treatment fields and boost-treatment have be end up same total volume as original schedule, where preceded treatment. These reductions corresponding weighting factors been calculated using linear-quadratic (LQ) model concept Normalized Total Dose (NTD). Relative (RNTD) distributions were computed evaluate resulting respect acute late normal tissue damage tumor control. For example prostatic cancer on basis NTD damage. oropharyngeal was used determine factors. In this last a theoretical sparing can demonstrated. A second advantage is that megavoltage images large facilitates determination position patient small fields.