On-site SEM and nanomechanical properties of human OI bone
作者： Chunju Gu , Dinesh R. Katti , Kalpana S. Katti
关键词:
摘要: Modulus mapping and on-site field emission-scanning electron microscopy (FE-SEM) nanoindentation are both applied for the first time on ‘undisturbed’ healthy human osteogenesis imperfecta (OI) cortical bones in this work. reveals elastic moduli of hydroxyapatite collagen to be 189·9 2·4 GPa normal bone 294·7 GPa 2·9 GPa OI respectively. also indicates a spatial variation consistent with distribution mineralized fibril extrafibrillar mineral. The diameter fibers size mineral crystals observed smaller, crystal is less anisotropic than those from bone. median sample greater On-site FE-SEM existence highly inner ring higher adjacent Haversian canal that elast...
sci-hub.se 参考文章(86)
Naoki Sasaki, Ayano Tagami, Toshiharu Goto, Masahiro Taniguchi, Mitsuo Nakata, Kunio Hikichi, Atomic force microscopic studies on the structure of bovine femoral cortical bone at the collagen fibril-mineral level. Journal of Materials Science: Materials in Medicine. ,vol. 13, pp. 333- 337 ,(2002) , 10.1023/A:1014079421895
John D. Currey, Jae-Young Rho, George M. Pharr, Peter Zioupos, The anisotropic Young's modulus of equine secondary osteones and interstitial bone determined by nanoindentation The Journal of Experimental Biology. ,vol. 204, pp. 1775- 1781 ,(2001) , 10.1242/JEB.204.10.1775
Ulrich Vetter, Mary Ann Weis, Martin Mörike, Edward David Eanes, David Rodney Eyre, Collagen crosslinks and mineral crystallinity in bone of patients with osteogenesis imperfecta Journal of Bone and Mineral Research. ,vol. 8, pp. 133- 137 ,(2009) , 10.1002/JBMR.5650080203
Nancy E Lane, Wei Yao, John H Kinney, Gunnard Modin, Mehdi Balooch, Thomas J Wronski, Both hPTH(1-34) and bFGF increase trabecular bone mass in osteopenic rats but they have different effects on trabecular bone architecture. Journal of Bone and Mineral Research. ,vol. 18, pp. 2105- 2115 ,(2003) , 10.1359/JBMR.2003.18.12.2105
P. Fratzl, H. S. Gupta, E. P. Paschalis, P. Roschger, Structure and mechanical quality of the collagen–mineral nano-composite in bone Journal of Materials Chemistry. ,vol. 14, pp. 2115- 2123 ,(2004) , 10.1039/B402005G
U Vetter, ED Eanes, JB Kopp, JD Termine, P Gehron Robey, None, Changes in apatite crystal size in bones of patients with osteogenesis imperfecta. Calcified Tissue International. ,vol. 49, pp. 248- 250 ,(1991) , 10.1007/BF02556213
Marcel E. Roy, Jae-Young Rho, Ting Y. Tsui, Neal D. Evans, George M. Pharr, Mechanical and morphological variation of the human lumbar vertebral cortical and trabecular bone. Journal of Biomedical Materials Research. ,vol. 44, pp. 191- 197 ,(1999) , 10.1002/(SICI)1097-4636(199902)44:2<191::AID-JBM9>3.0.CO;2-G
Rahul Bhowmik, Kalpana S. Katti, Dinesh R. Katti, Mechanics of molecular collagen is influenced by hydroxyapatite in natural bone Journal of Materials Science. ,vol. 42, pp. 8795- 8803 ,(2007) , 10.1007/S10853-007-1914-1
Neal S. Fedarkcv, Ulrich Vetter, Pamela Gehron Robey, The bone cell biology of osteogenesis imperfecta Connective Tissue Research. ,vol. 31, pp. 269- 273 ,(1995) , 10.3109/03008209509010821
Richard Mendelsohn, Eleftherios P. Paschalis, Adele L. Boskey, Infrared spectroscopy, microscopy, and microscopic imaging of mineralizing tissues: spectra-structure correlations from human iliac crest biopsies. Journal of Biomedical Optics. ,vol. 4, pp. 14- 21 ,(1999) , 10.1117/1.429916