[(Quality of semen in patients with Crohn's disease)]

摘要: Some reports point to an inhibitory effect of Salzosulfapyridin (SASP) in spermatogenesis. It is not clear whether inflammatory bowel disease itself influencing the maturation spermatozoa and activity reflected by changes sperm development. 27 patients with Crohn's were studied. 6 without treatment, 10 received SASP, 11 had both, SASP methylprednisolone. The analysis was different between untreated treated patients. Sperm density equal both groups while number mobile mature sperms slightly but significantly decreased. quality on lower limit normal. In contrast, all combined treatment methylprednisolone pathological findings density, morphology motility. index latter group higher than or treatment. concluded that are necessarily consequence seems likely plays a role spermatogenesis derangements increase severity disease.